Affiliate Marketing Secrets

I am worried about my computer getting hacked. Is there any way anyone can hack me without me having to click a link or open a tainted email?
I never click on emails and I only visit safe websites. I have a malware scanner and I run once per day plus anti virus and I have all of my internet settings on high alert. I am also using Firefox.
Can people hack you and access your files without you having to click something?