Affiliate Marketing Secrets

I want to create a niche website for google adsense, please tell me the best plan for it.
When i say ‘plan’ i mean:
-what seo practices?
-Should i use a static website or a cms one?
-How to place ads for best results?
-Can adsense and affiliate marketing work together?
-And what things can harm my site?
-and all the other brief information in need to know?
Please guys i am stuck here 🙁
Will be very thankful for the help. 🙂

I want to create a quality content niche oriented website using wordtracker’s keyword tools, on a CMS platform and will monetize my website by displaying google ads and by affiliate marketing.
Please tell me what things i need to know to fulfill my job as i am all new to this field.
Also tell me what SEO practices i need do for my website.